Calorie-restricted diets have been proven to increase the lifespan and healthspan of everything from monkeys to yeasts – as long as there is no malnutrition. And while no long-interval research has shown the advantages of calorie restriction on human life, shorter-term studies recommend that it does improve wellbeing.
Human bodies monitor and sense the quantity of nutrients available via specific molecules in our cells. Relying on the amount of food we eat, these molecules squeeze our metabolism to regulate how we use the available vitamins. One of these units is an enzyme known as TOR.
When there is plenty of food, the TOR enzyme guides cells in the body to grow. If there’s less food, TOR tells the body to be on alert—a state that scientists call a “mild stress response.”
Many studies have proven that when animals eat plenty of food, particularly for prolonged durations, TOR senses this and their lifespan gets shorter.
TOR enzyme is primarily activated when cells sense large quantities of amino acids or protein. A protein-restricted food regimen, without malnutrition, can have the same results on the metabolism and lifespan of lab animals as a calorie-restricted food plan.
So there may be a connection between what we eat, how it is sensed by our body, and the danger of neurodegenerative condition. Scientists are searching for different possibilities to prevent neurodegeneration. If more protein suggests more active TOR, humans might either change their food regimen, safely or develop a drug that tricks the body into thinking it’s getting less protein.